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Here's a selection of information from patients & professionals to better understand Behçet’s Syndrome .

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All Behçet’s Syndrome Documents

  • Safe, Rapid-onset, and Sustained Biological Activity of IL-1bRegulating Antibody XOMA 052 in Resistant Uveitis of Behcet’s Disease: Results of a Pilot Trial

    PDF Poster

    Author/Foundation: Ahmet Guel,Bahar Artim Esen,Alan Solinger,Linda Giustino,Charles Dinarello,and Ilknur Tugal-Tutkun

    Year of publication: 2010, English

    Tags: Treatments

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  • Pulmonary involvement in Behcet’s disease: a positive single-center experience with the use of immunosuppressive therapy

    From: Jornal Brasileiro de Pneumologia Objective: Behcet’s syndrome, or Behcet’s disease (BD), is a multisystem pathology, and survival is related to pulmonary involvement. However, it appears that different treatments correlate with different prognoses. The aim of this study was to evaluate clinical and tomographic evolution, as well as the survival, of patients with BD-related pulmonary involvement. Methods: A retrospective review of our experience with pulmonary manifestations in patients with BD treated at our institution between January 1, 1988 and April 30, 2006. The clinical, radiological, treatment and survival data were obtained from medical charts. Results: We identified 9 patients with BD-related pulmonary involvement. The mean age was 34 ± 11.5 years, and 7 of the patients were male. The radiological findings were as follows: pulmonary artery aneurysm (PAA) in 8 patients; pulmonary embolism in 3 (translating to an incidence of 5.11 cases/100 patient-years); alveolar hemorrhage in one; and pulmonary hypertension in one. The treatment consisted of immunosuppression with prednisone plus chlorambucil (or cyclophosphamide or mycophenolate mofetil) in all patients, with partial or complete resolution of the PAAs. One patient with a PAA and pulmonary hypertension also received sildenafil and warfarin, with good clinical and tomographic response (the first report in the English literature). In our sample, the mean duration of the follow-up period was 6.52 years. The three-year survival rate was 88.8%, as was the five-year survival rate. Conclusions: Patients with BD-related pulmonary involvement can present good survival with immunosuppressive therapy, and BD should be borne in mind as a possible cause of pulmonary hypertension and alveolar hemorrhage.

    Author/Foundation: Alfredo Nicodemos Cruz Santana, Telma Antunes, et al.

    Year of publication: 2008, English

    Tags: Treatments

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  • Behçet’s Disease: an Insight from a Cardiologist’s Point of View

    From: The Open Cardiovascular Medicine Journal Abstract: Behçet's disease (BD) is an enigmatic inflammatory disorder, with vasculitis (perivasculitis) underlying pathophysiology of its multisystemic affections. Venous pathology and thrombotic complications are hallmarks of BD. However, it has been increasingly recognized that cardiac involvement and arterial complications (aneurysms, pseudoaneurysms, rupture and thrombosis) are important part of the course of BD. Pericarditis, myocardial (diastolic and/or systolic dysfunction), valvular and coronary (thrombosis, aneurysms, rupture) involvement, intracardiac thrombi (predominantly right-sided) are, probably, the most frequent cardiac manifestations. Treatment of cardiovascular involvement in BD is largely empirical and aimed at suppression of vasculitis. The most challenging seems to be the treatment of arterial aneurysms and thromboses due to the associated risk of bleeding. Cardiologists should always bear in mind potential threats of (a)symptomatic cardiovascular involvement in BD.

    Author/Foundation: Giuseppe Cocco, and Armen Yuri Gasparyan

    Year of publication: 2010, English

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  • IMPEGNO OCULARE IN CORSO DI MORBO DI BEHÇET: ATTUALITÀ NEL TRATTAMENTO (IT)

    Il Morbo di Behcet (MB) è una patologia multisistemica ad eziologia sconosciuta causata da un processo flogistico cronico che può coinvolgere vasi arteriosi e venosi di qualsiasi calibro. Il quadro clinico è classicamente rappresentato dalla presenza di aftosi orale ricorrente, aftosi genitale, lesioni cutanee e impegno oculare, a cui si associano con frequenza variabile altre manifestazioni cliniche estremamente eterogenee, che coinvolgono le articolazioni, l’apparato gastroenterico, l’apparato vascolare, il sistema nervoso centrale e periferico. Il coinvolgimento oculare rappresenta una delle complicanze più temibili della malattia, tanto da costituire, se non precocemente riconosciuto, una delle principali cause di morbilità.

    Author/Foundation: Michele Figus, Marco Nardi

    Year of publication: 2010, Italian

    Tags: Italiano

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  • LA MALATTIA DI BEHCET (IT)

    2° Divisione Medicina Interna. Azienda Ospedaliera S.Maria Nuova. Reggio Emilia La sindrome di Behçet (SD) è una vasculite sistemica ricorrente, multisintomatica, a decorso cronico ed etiologia sconosciuta. Questa malattia è in grado di colpire tutti gli organi sia simultaneamente che susseguentemente e talora presenta una prognosi severa correlata all’organo maggiormente colpito. La SB è stata studiata in modo sistematico per molti anni e recentemente sono stati individuate molte informazioni che si riferiscono alla patogenesi, agli aspetti clinici, alla malattia durante la gravidanza e l’infanzia , alla sua prognosi ed alla terapia.

    Author/Foundation: Dott.ssa P.Casoli, Dott.B.Tumiati

    Year of publication: 2010, Italian

    Tags: Italiano

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  • The 14th International Conference on Behçet’s Disease Queen Mary University, London, 8–10 July 2010

    The 14th International Conference on Behçet’s Disease was attended by around 300 delegates. Twenty-five abstracts were presented orally and more than 150 as posters. There were also a number of presentations from outside speakers and ISBD invited speakers.

    Author/Foundation: Behçet’s Syndrome Society

    Year of publication: 2010, English

    Tags: Meetings

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  • SIMBA Uscita no. 2 dicembre 2010

    http://www.behcet.it/index.php

    Author/Foundation: SIMBA

    Year of publication: 2010, Italian

    Tags: Italiano

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  • Qué es La Enfermedad de Behçet? (ES)

    Foletto PDF

    Author/Foundation: Sociedad Española de Reumatología

    Year of publication: 2010, Spanish

    Tags: Española

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